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In Vivo Whole Animal Fluorescence Imaging of a Microparticle-Based Oral Vaccine Containing (CuInSexS2-x)/ZnS Core/Shell Quantum Dots

Identifieur interne : 000B20 ( Main/Repository ); précédent : 000B19; suivant : 000B21

In Vivo Whole Animal Fluorescence Imaging of a Microparticle-Based Oral Vaccine Containing (CuInSexS2-x)/ZnS Core/Shell Quantum Dots

Auteurs : RBID : Pascal:13-0330718

Descripteurs français

Pascal (Inist)
- In vivo, Fluorescence, Formation image, Microparticule, Semiconducteur II-VI, Sulfure de zinc, Sulfure de cuivre, Indium, Séléniure, Rayonnement IR proche, Spectre IR proche, Spectre IR, Rendement quantique, Nanocristal, Nanomatériau, Encapsulation, Point quantique, Matériau fluorescent, 7830N, 8107B, 8107T, 8535B, Structure coeur coque.

English descriptors

KwdEn :
- Copper sulfide, Core shell structure, Encapsulation, Fluorescence, Fluorescent material, II-VI semiconductors, Imaging, In vivo, Indium, Infrared spectra, Microparticles, Nanocrystal, Nanostructured materials, Near infrared radiation, Near infrared spectrum, Quantum dots, Quantum yield, Selenides, Zinc sulfide.

Abstract

Zinc sulfide-coated copper indium sulfur selenide (CuInSe_xS_2-x/ZnS core/shell) nanocrystals were synthesized with size-tunable red to near-infrared (NIR) fluorescence with high quantum yield (40%) in water. These nanocrystals were tested as an imaging agent to track a microparticle-based oral vaccine administered to mice. Poly(lactic-co-glycolic acid) (PLGA) microparticle-encapsulated CuInSe_xSe_2-x/ZnS quantum dots were orally administered to mice and were found to provide a distinct visible fluorescent marker in the gastrointestinal tract of living mice.

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Pascal:13-0330718

Le document en format XML

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S<sub>2-x</sub>
)/ZnS Core/Shell Quantum Dots</title>
<author><name sortKey="Panthani, Matthew G" uniqKey="Panthani M">Matthew G. Panthani</name>
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<author><name sortKey="Khan, Tarik A" uniqKey="Khan T">Tarik A. Khan</name>
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<author><name sortKey="Maynard, Jennifer A" uniqKey="Maynard J">Jennifer A. Maynard</name>
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<author><name sortKey="Korgel, Brian A" uniqKey="Korgel B">Brian A. Korgel</name>
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<publicationStmt><idno type="inist">13-0330718</idno>
<date when="2013">2013</date>
<idno type="stanalyst">PASCAL 13-0330718 INIST</idno>
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</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Copper sulfide</term>
<term>Core shell structure</term>
<term>Encapsulation</term>
<term>Fluorescence</term>
<term>Fluorescent material</term>
<term>II-VI semiconductors</term>
<term>Imaging</term>
<term>In vivo</term>
<term>Indium</term>
<term>Infrared spectra</term>
<term>Microparticles</term>
<term>Nanocrystal</term>
<term>Nanostructured materials</term>
<term>Near infrared radiation</term>
<term>Near infrared spectrum</term>
<term>Quantum dots</term>
<term>Quantum yield</term>
<term>Selenides</term>
<term>Zinc sulfide</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>In vivo</term>
<term>Fluorescence</term>
<term>Formation image</term>
<term>Microparticule</term>
<term>Semiconducteur II-VI</term>
<term>Sulfure de zinc</term>
<term>Sulfure de cuivre</term>
<term>Indium</term>
<term>Séléniure</term>
<term>Rayonnement IR proche</term>
<term>Spectre IR proche</term>
<term>Spectre IR</term>
<term>Rendement quantique</term>
<term>Nanocristal</term>
<term>Nanomatériau</term>
<term>Encapsulation</term>
<term>Point quantique</term>
<term>Matériau fluorescent</term>
<term>7830N</term>
<term>8107B</term>
<term>8107T</term>
<term>8535B</term>
<term>Structure coeur coque</term>
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<front><div type="abstract" xml:lang="en">Zinc sulfide-coated copper indium sulfur selenide (CuInSe<sub>x</sub>
S<sub>2-x</sub>
/ZnS core/shell) nanocrystals were synthesized with size-tunable red to near-infrared (NIR) fluorescence with high quantum yield (40%) in water. These nanocrystals were tested as an imaging agent to track a microparticle-based oral vaccine administered to mice. Poly(lactic-co-glycolic acid) (PLGA) microparticle-encapsulated CuInSe<sub>x</sub>
Se<sub>2-x</sub>
/ZnS quantum dots were orally administered to mice and were found to provide a distinct visible fluorescent marker in the gastrointestinal tract of living mice.</div>
</front>
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<fA08 i1="01" i2="1" l="ENG"><s1>In Vivo Whole Animal Fluorescence Imaging of a Microparticle-Based Oral Vaccine Containing (CuInSe<sub>x</sub>
S<sub>2-x</sub>
)/ZnS Core/Shell Quantum Dots</s1>
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<fA11 i1="01" i2="1"><s1>PANTHANI (Matthew G.)</s1>
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<fA11 i1="02" i2="1"><s1>KHAN (Tarik A.)</s1>
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<fA11 i1="03" i2="1"><s1>REID (Dariya K.)</s1>
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<fA11 i1="05" i2="1"><s1>RASCH (Michael R.)</s1>
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<fA14 i1="01"><s1>Department of Chemical Engineering, Texas Materials Institute, and Center for Nano- and Molecular Science and Technology, The University of Texas at Austin</s1>
<s2>Austin, Texas 78712</s2>
<s3>USA</s3>
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<fC01 i1="01" l="ENG"><s0>Zinc sulfide-coated copper indium sulfur selenide (CuInSe<sub>x</sub>
S<sub>2-x</sub>
/ZnS core/shell) nanocrystals were synthesized with size-tunable red to near-infrared (NIR) fluorescence with high quantum yield (40%) in water. These nanocrystals were tested as an imaging agent to track a microparticle-based oral vaccine administered to mice. Poly(lactic-co-glycolic acid) (PLGA) microparticle-encapsulated CuInSe<sub>x</sub>
Se<sub>2-x</sub>
/ZnS quantum dots were orally administered to mice and were found to provide a distinct visible fluorescent marker in the gastrointestinal tract of living mice.</s0>
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<s2>NA</s2>
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<s5>30</s5>
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<fN44 i1="01"><s1>OTO</s1>
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In Vivo Whole Animal Fluorescence Imaging of a Microparticle-Based Oral Vaccine Containing (CuInSexS2-x)/ZnS Core/Shell Quantum Dots

In Vivo Whole Animal Fluorescence Imaging of a Microparticle-Based Oral Vaccine Containing (CuInSexS2-x)/ZnS Core/Shell Quantum Dots

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Abstract

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